Browsing by Author "Özkay, Yusuf"
Now showing items 1-2 of 2
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Design, synthesis, and biological activity of novel dithiocarbamate-methylsulfonyl hybrids as carbonic anhydrase inhibitors
Osmaniye, Derya; Türkeş, Cüneyt; Demir, Yeliz; Özkay, Yusuf; Kaplancıklı, Zafer Asım; Beydemir, Şükrü (Wiley, 2022)Carbonic anhydrase (CA) enzymes are involved in many physiological events. These enzymes, which contain Zn2+ in their structure, can be easily inhibited by dithiocarbamate compounds. In addition, CA enzyme inhibitory ... -
Synthesis, investigation of biological effects and in silico studies of new benzimidazole derivatives as aromatase inhibitors
Sağlık, Begüm Nurpelin; Şen, Ahmet Mücahit; Evren, Asaf Evrim; Acar-Çevik, Ulviye; Osmaniye, Derya; Kaya-Çavuşoğlu, Betül; Levent, Serkan; Karaduman, Abdullah Burak; Özkay, Yusuf; Kaplancıklı, Zafer Asım (Walter de Gruyter, 2020)Inhibition of aromatase enzymes is very important in the prevention of estrogen-related diseases and the regulation of estrogen levels. Aromatase enzyme is involved in the final stage of the biosynthesis of estrogen, in ...
