Browsing by Author "Küfrevioğlu, Ömer İrfan"

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Calcium Channel Blockers: The Effect of Glutathione S-Transferase Enzyme Activity and Molecular Docking Studies

Türkeş, Cüneyt; Öztürk, Kesebir; Demir, Yeliz; Küfrevioğlu, Ömer İrfan; Beydemir, Şükrü (Wiley, 2021)

Recently, as a drug target in cancer treatment, the superfamily of glutathione S-transferase (GSTs, EC 2.5.1.18) have been invited considerable interest by scientists. In particular, as they are overexpressed in many human ...
In vitro and in silico interactions of antiulcer, glucocorticoids and urological drugs on human carbonic anhydrase I and II isozymes

Güller, Uğur; Beydemir, Şükrü; Küfrevioğlu, Ömer İrfan (Wiley, 2022)

Carbonic anhydrases (CAs, Enzyme Commission 4.2.1.1) convert carbon dioxide to bicarbonate in metabolism and use Zn2+ ions as a cofactor for their catalytic activity. The activators or inhibitors of CA-I and CA-II, which ...