WoS İndeksli Yayınlar Koleksiyonu
Recent Submissions
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An examination of the Fisher Hypothesis: the case of Turkey
(Routledge Journals, 2008)This study examines the famous Fisher Hypothesis (FH) for Turkey. FH asserts that nominal interest rates adjust on a one-to-one basis to expected changes in inflation rates. Using the Johansen cointegration method for the ... -
Influence of SiC addition on tribological properties of SiAlON
(Elsevier, 2011)The tribological properties of gas pressure sintered SiAlON and its composite with 18 wt% silicon carbide (SiC) against two different mating materials, i.e., alumina and SiAlON are evaluated. SiAlON and SiAlON–18%SiC ... -
On the quaternionic B-2 slant helices in the semi-Euclidean space E-2(4)
(Elsevier, 2012)In this paper, we studied quaternionic slant helices which we called semi-real quaternionic B2 slant helix in four dimensional semi-Euclidean space E4 2. Also we define the harmonic curvature functions for semi-real ... -
The influence of zeolite and powdered Bayburt stones on the water transport kinetics and mechanical properties of hydrated lime mortars
(Elsevier, 2015)The purpose of this paper is an investigation of the possible role of zeolite and powdered Bayburt stones on the fresh and hardened properties of hydrated lime (CL90) mortars. Parameters studied in this paper form the ... -
A comparative study on corrosion of Mg-Al-Si alloys
(Elsevier, 2017)Corrosion behavior of various Mg−Al−Si alloys (AS11, AS21, AS41, AS61 and AS91 series), cast under the same cooling conditions and controlled alloying composition, was investigated systematically. Optical microscopy and ... -
Comparative study on corrosion behaviors of Mg-Al-Zn alloys
(Elsevier, 2018)A comparative study on corrosion behaviors of various Mg−Al−Zn alloys (AZ21, AZ41, AZ61 and AZ91 series, cast under same cooling conditions and controlled alloying composition) was carried out. Scanning electron microscopy ... -
Novel inhibitors with sulfamethazine backbone: synthesis and biological study of multi-target cholinesterases and alpha-glucosidase inhibitors
(Taylor & Francis, 2022)The underlying cause of many metabolic diseases is abnormal changes in enzyme activity in metabolism. Inhibition of metabolic enzymes such as cholinesterases (ChEs; acetylcholinesterase, AChE and butyrylcholinesterase, ... -
Synthesis, Characterization, and Inhibition Study of Novel Substituted Phenylureido Sulfaguanidine Derivatives as alpha-Glycosidase and Cholinesterase Inhibitors
(Wiley, 2021)A series of six N-carbamimidoyl-4-(3-substituted phenylureido)benzenesulfonamide derivatives were synthesized by reaction of sulfaguanidine with aromatic isocyanates. In vitro and in silico inhibitory effects of the novel ... -
Biological effects of bis-hydrazone compounds bearing isovanillin moiety on the aldose reductase
(Academic Press-Elsevier Science, 2021)Aldose reductase (ALR2), one of the metabolically important enzymes, catalyzes the formation of sorbitol from glucose in the polyol pathway. ALR2 inhibition is required to prevent diabetic complications. In the present study, ... -
A novel series of thiosemicarbazone hybrid scaffolds: Design, synthesis, DFT studies, metabolic enzyme inhibition properties, and molecular docking calculations
(Elsevier, 2023)The fourteen new thiosemicarbazone derivatives of Schiff base were synthesized from the condensation reactions of two different aldehydes (3–hydroxy-4-methoxhybenzaldehyde and 3-ethoxhy-4- hydroxybenzaldehyde) with various ... -
Enzyme inhibition, molecular docking, and density functional theory studies of new thiosemicarbazones incorporating the 4-hydroxy-3,5-dimethoxy benzaldehyde motif
(Wiley, 2023)New Schiff base‐bearing thiosemicarbazones (1–13) were obtained from 4‐hydroxy‐3, 5‐dimethoxy benzaldehyde and various isocyanates. The structures of the synthesized molecules were elucidated in detail. Density functional ... -
Benzenesulfonamide derivatives as potent acetylcholinesterase, alpha-glycosidase, and glutathione S-transferase inhibitors: biological evaluation and molecular docking studies
(Taylor & Francis, 2020)Sulfonamide derivatives exhibit a wide biological activity and can function as potential medical molecules in the development of a drug. Studies have reported that the compounds have an effect on many enzymes. In this ... -
Design, synthesis, characterization, in vitro and in silico evaluation of novel imidazo[2,1-b][1,3,4]thiadiazoles as highly potent acetylcholinesterase and non-classical carbonic anhydrase inhibitors
(Academic Press-Elsevier Science, 2021)Imidazole and thiadiazole derivatives display an extensive application in pharmaceutical chemistry, and they have been investigated as bioactive molecules for medicinal chemistry purposes. Classical carbonic anhydrase (CA) ... -
Synthesis and characterization of novel acyl hydrazones derived from vanillin as potential aldose reductase inhibitors
(Springer, 2022)In the polyol pathway, aldose reductase (AR) catalyzes the formation of sorbitol from glucose. In order to detoxify some dangerous aldehydes, AR is essential. However, due to the efects of the active polyol pathway, AR ... -
Exploration of Some Bis-Sulfide and Bis-Sulfone Derivatives as Non-Classical Aldose Reductase Inhibitors
(Wiley, 2023)Aldose reductase (AR, ALR2; EC 1.1.1.21), an enzyme that converts glucose to fructose on the polyol pathway, is an important member of the Aldo-keto reductase superfamily. ALR2 is part of the rate-limiting step, which is ... -
Biological evaluation and in silico study of benzohydrazide derivatives as paraoxonase 1 inhibitors
(Wiley, 2022)Serum paraoxonase 1 (PON1) is found in all mammalian species and is a calcium-dependent hydrolytic enzyme. PON1 hydrolyze several substrates, including carbonates, esters, and organophosphates. In the current study, we ... -
Synthesis, biological evaluation, and in silico study of novel library sulfonates containing quinazolin-4(3H)-one derivatives as potential aldose reductase inhibitors
(Wiley, 2022)A series of novel sulfonates containing quinazolin-4(3H)-one ring derivatives was designed to inhibit aldose reductase (ALR2, EC 1.1.1.21). Novel quinazolinone derivatives (1–21) were synthesized from the reaction of ... -
Novel bis-ureido-substituted sulfaguanidines and sulfisoxazoles as carbonic anhydrase and acetylcholinesterase inhibitors
(Springer, 2022)To discover alternative substances to compounds used to treat many diseases, especially treating Alzheimer’s disease (AD) and Parkinson’s disease targeting carbonic anhydrase (hCA) and acetylcholinesterase (AChE) enzymes, ... -
Cytotoxic effect, enzyme inhibition, and in silico studies of some novel N-substituted sulfonyl amides incorporating 1,3,4-oxadiazol structural motif
(Springer, 2022)The acetylcholinesterase and carbonic anhydrase inhibitors (AChEIs and hCAIs) remain key therapeutic agents for many bioactivities such as anti-Alzheimer and antiobesity antiepileptic, anticancer, antiinfective, antiglaucoma, ... -
N-substituted phthalazine sulfonamide derivatives as non-classical aldose reductase inhibitors
(Wiley, 2022)Aldose reductase (AR, AKR1B1; EC 1.1.1.21) is an aldo-keto reductase that has been widely investigated as an enzyme crucially involved in the pathogenesis of several chronic complications, including nephropathy, neuropathy, ...
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