Browsing by Author "Yakan, Hasan"
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Enzyme inhibition, molecular docking, and density functional theory studies of new thiosemicarbazones incorporating the 4-hydroxy-3,5-dimethoxy benzaldehyde motif
Demir, Yeliz; Türkeş, Cüneyt; Çavuş, Muhammet Serdar; Erdoğan, Musa; Muğlu, Halit; Yakan, Hasan; Beydemir, Şükrü (Wiley, 2023)New Schiff base‐bearing thiosemicarbazones (1–13) were obtained from 4‐hydroxy‐3, 5‐dimethoxy benzaldehyde and various isocyanates. The structures of the synthesized molecules were elucidated in detail. Density functional ... -
A novel series of thiosemicarbazone hybrid scaffolds: Design, synthesis, DFT studies, metabolic enzyme inhibition properties, and molecular docking calculations
Yakan, Hasan; Muğlu, Halit; Türkeş, Cüneyt; Demir, Yeliz; Erdoğan, Musa; Çavuş, Muhammet Serdar; Beydemir, Şükrü (Elsevier, 2023)The fourteen new thiosemicarbazone derivatives of Schiff base were synthesized from the condensation reactions of two different aldehydes (3–hydroxy-4-methoxhybenzaldehyde and 3-ethoxhy-4- hydroxybenzaldehyde) with various ...