Browsing by Author "Necip, Adem"

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Mannich reaction derived novel boron complexes with amine-bis(phenolate) ligands: Synthesis, spectroscopy and in vitro/in silico biological studies

Kılıç, Ahmet; Beyazsakal, Levent; Işık, Mesut; Türkeş, Cüneyt; Necip, Adem; Takım, Kasım; Beydemir, Şükrü (Elsevier, 2020)

The amine-bis(phenolate) ligands was prepared through a Mannich reaction utilizing two equivalents of 2,4-di-tert-butylphenol or 4-tert-butylphenol, two equivalents of formaldehyde and a single equivalent of 2-aminoethyl ...
Novel bis-ureido-substituted sulfaguanidines and sulfisoxazoles as carbonic anhydrase and acetylcholinesterase inhibitors

Lolak, Nebih; Akoçak, Süleyman; Durgun, Mustafa; Duran, Hatice Esra; Necip, Adem; Türkeş, Cüneyt; Işık, Mesut; Beydemir, Şükrü (Springer, 2022)

To discover alternative substances to compounds used to treat many diseases, especially treating Alzheimer’s disease (AD) and Parkinson’s disease targeting carbonic anhydrase (hCA) and acetylcholinesterase (AChE) enzymes, ...