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dc.contributor.authorŞahin, Samet
dc.contributor.authorÇağlayan, Mustafa Oğuzhan
dc.contributor.authorÜstündağ, Zafer
dc.date.accessioned2022-10-06T07:38:37Z
dc.date.available2022-10-06T07:38:37Z
dc.date.issued2020en_US
dc.identifier.citationŞahin, S., Caglayan, M. O., & Üstundağ, Z. (2020). A review on nanostructure-based mercury (II) detection and monitoring focusing on aptamer and oligonucleotide biosensors. Talanta, 121437.en_US
dc.identifier.issn0039-9140
dc.identifier.issn1873-3573
dc.identifier.urihttps://doi.org/10.1016/j.talanta.2020.121437
dc.identifier.urihttps://hdl.handle.net/11552/2624
dc.description.abstractHeavy metal ion pollution is a severe problem in environmental protection and especially in human health due to their bioaccumulation in organisms. Mercury (II) (Hg2+), even at low concentrations, can lead to DNA damage and give permanent harm to the central nervous system by easily passing through biological membranes. Therefore, sensitive detection and monitoring of Hg2+ is of particular interest with significant specificity. In this review, aptamer-based strategies in combination with nanostructures as well as several other strategies to solve addressed problems in sensor development for Hg2+ are discussed in detail. In particular, the analytical performance of different aptamer and oligonucleotide-based strategies using different signal improvement approaches based on nanoparticles were compared within each strategy and in between. Although quite a number of the suggested methodologies analyzed in this review fulfills the standard requirements, further development is still needed on real sample analysis and analytical performance parameters.en_US
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.identifier.doi10.1016/j.talanta.2020.121437en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAptamersen_US
dc.subjectBiosensorsen_US
dc.subjectHg2+ Detectionen_US
dc.subjectNanomaterialsen_US
dc.subjectOligonucleotide Probesen_US
dc.titleA review on nanostructure-based mercury (II) detection and monitoring focusing on aptamer and oligonucleotide biosensorsen_US
dc.typearticleen_US
dc.relation.ispartofTalantaen_US
dc.departmentFakülteler, Mühendislik Fakültesi, Biyomühendislik Bölümüen_US
dc.authorid0000-0002-0568-4283en_US
dc.authorid0000-0002-7265-1094en_US
dc.identifier.volume220en_US
dc.identifier.issue121437en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.relation.indexPubMeden_US
dc.relation.indexScopusen_US
dc.relation.indexWoSen_US
dc.relation.indexWoS - Science Citation Index Expandeden_US
dc.contributor.institutionauthorŞahin, Samet
dc.contributor.institutionauthorÇağlayan, Mustafa Oğuzhan
dc.description.wospublicationidWOS:000571902700009en_US
dc.description.scopuspublicationid1-s2.0-S0039914020307281en_US
dc.description.pubmedpublicationidPMID: 32928439en_US
dc.authorwosidP-6962-2016en_US
dc.authorwosidAAD-7966-2020en_US
dc.description.wosqualityQ1en_US


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