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Identification of a new class of potent aldose reductase inhibitors: Design, microwave-assisted synthesis, in vitro and in silico evaluation of 2-pyrazolines
(Elsevier, 2021)
Aldose reductase (AR) acts as a multi-disease target for the design and development of therapeutic agents for the management of diabetic complications as well as non-diabetic diseases. In the search for potent AR inhibitors, ...
An extensive research on aldose reductase inhibitory effects of new 4H-1,2,4-triazole derivatives
(Elsevier, 2021)
Aldose reductase (AR) is a key enzyme, which triggers the excessive accumulation of sorbitol in insulin independent tissues leading to severe diabetes-induced microvascular complications. Substantial evidence has proven ...
Novel benzoic acid derivatives: Synthesis and biological evaluation as multitarget acetylcholinesterase and carbonic anhydrase inhibitors
(Wiley, 2020)
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by dementia, memory impairment, cognitive dysfunction, and speech impairment. The utility of cholinergic replacement by acetylcholinesterase (AChE) ...
Novel metabolic enzyme inhibitors designed through the molecular hybridization of thiazole and pyrazoline scaffolds
(Wiley, 2021)
New hybrid thiazolyl-pyrazoline derivatives (4a-k) were obtained through a facile and versatile synthetic procedure, and their inhibitory effects on the human carbonic anhydrase (hCA) isoforms I and II as well as on ...
The photosensitive activity of organic/inorganic hybrid devices based on Aniline Blue dye: Au nanoparticles (AB@Au NPs)
(Elsevier, 2021)
In this study, Aniline Blue (AB) synthetic triarylmethane dye and AB:Au NPs mixture films were deposited
on n-Si by spin coating technique to form an organic/inorganic hybrid electro-optic device. Thus,
Co/AB/n-Si (named ...
Two Pseudo‑Common Vectors for Pattern Recognition
(Springer Heidelberg, 2020)
In this paper, the mathematical model used in fnding the common vectors of classes in pattern recognition problems is
reconsidered to obtain possible alternative solutions for the common vectors. Since the number of ...
Purification of the phytase enzyme fromLactobacillus plantarum: The effect on pansy growth and macro-micro element content
(Wiley, 2021)
In the present study, the phytase enzyme was purified fromLactobacillus plantarumwith a 3.08% recovery, 9.57-purification fold, and with a specific activity of 278.82 EU/mg protein. Then, the effects of the 5 EU and 10 EU ...
Great enhancement of two photon absorption cross section value by intramolecular charge transfer in newly synthesized triphenylamine-BODIPY derivative
(Elsevier, 2021)
Novel borondipyrromethene (BODIPY) compound without a −8 (meso) substituent containing triphenylamine moieties via Suzuki-Miyaura coupling was designed and synthesized to enhance two photon absorption (TPA) property. The ...
The modification of the characteristics of ZnO nanofibers by TCNQ doping content
(Springer, 2021)
In this study, the electrical properties of an Al/p-Si metal/semiconductor
photodiodes with Tetracyanoquinodimethane–Polyvinyl chloride (TCNQ–PVC)
and PVC–TCNQ:ZnO interfacial layers were investigated. Growing of ...
Extended exergy analysis of a solar driven water production plant via reverse osmosis
(Pergamon-Elsevier Science, 2021)
Water scarcity and contamination of available water are becoming one of the most complex problems worldwide and they compromise economic development, global sustainability, and human supply, among others. Water is required ...
