Amygdalin (Vitamin B17) Effect on Glioblastoma: Focus on Oxidant Capacity and Antioxidant Status

dc.contributor.authorGenç, Sıdıka
dc.contributor.authorKarabulut, Kübra
dc.contributor.authorNiğde, Esmanur
dc.contributor.authorAydin, Yunus Emre
dc.contributor.authorAydın, Beyzanur
dc.contributor.authorAydın, Alperen Enes
dc.contributor.authorTaghizadehghalehjoughi, Ali
dc.date.accessioned2025-05-20T18:28:15Z
dc.date.issued2024
dc.departmentBilecik Şeyh Edebali Üniversitesi
dc.description.abstractObjective: Amygdalin (Vitamin B-17) is a type of vitamin, naturally found in many fruits and plants. The aim of the study was the evaluation of Amygdalin effect on the oxidant capacity and oxidant status of the T98G cancer cells. A T98G cell line was used in the study. Cell viability and oxidative stress evaluation were done. Methods: Amygdalin was used at 1, 4, and 8 µg/mL doses. TAC and TOS values were measured. Results: According to the result, amygdalin 8 µg/mL shows the highest anticancer effects. TAC level was 3.2 Trolox Equiv/L and TOS was 3.6 H2O2 Equiv/L. Conclusion: Vit B17 can increase oxidative stress in T98G cells and decrease cell viability
dc.identifier.doi10.62425/rtpharma.1523732
dc.identifier.endpage78
dc.identifier.issn2980-194X
dc.identifier.issue2
dc.identifier.startpage75
dc.identifier.urihttps://doi.org/10.62425/rtpharma.1523732
dc.identifier.urihttps://hdl.handle.net/11552/4121
dc.identifier.volume2
dc.language.isoen
dc.publisherAtaturk University
dc.relation.ispartofRecent Trends in Pharmacology
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_DergiPark_20250518
dc.subjectAmygdalin
dc.subjectTAC
dc.subjectTOS
dc.subjectMTT
dc.subjectT98G
dc.titleAmygdalin (Vitamin B17) Effect on Glioblastoma: Focus on Oxidant Capacity and Antioxidant Status
dc.typeResearch Article

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