Comparison of Ischemia-modified Albumin and Exercise Stress Test in Stable Angina Pectoris

Abstract

Objectives: We aimed to compare ischemia modified albumin (IMA) and exercise stress test to determine myocardial ischemia in stable angina pectoris and investigate the diagnostic value of IMA in non-exercised patients. Materials and Methods: One hundred and eight patients who applied to the cardiology outpatient clinic with chest pain and were diagnosed with ischemia on myocardial perfusion scintigraphy were included in the study. They were divided into groups with and without coronary artery disease (CAD) according to the results of coronary angiography and with and without ischemia according to the stress electrocardiogram (ECG) results. In addition, IMA levels of the patients were measured, and an exercise stress test was performed. Results: The IMA was found to be 1.06±0.23 in patients with CAD and 1.12±0.18 in patients without CAD (p=0.08). Statistically, between the groups, IMA determined no significant evidence for ischemia in stable angina pectoris. Conclusion: No significant difference was found between exercise ECG and IMA in the study of patient groups to determine myocardial ischemia in patients with stable angina pectoris. That is why it has been concluded that the measurement of IMA does not help determine myocardial ischemia in immobile patients and that it cannot be used in place of a stress ECG test.