ACTN3 RS1815739, PPARA RS4253778 VE IL6 RS1800795 GEN POLİMORFİZMLERİNİN VOLEYBOLCULARDA AEROBİK DAYANIKLILIK ÜZERİNE ETKİLERİNİN İNCELENMESİ

Abstract

Bu çalışmada voleybolcularda aerobik dayanıklılık ile ACTN3 rs1815739, PPARA rs4253778 ve IL-6 rs1800795 polimorfizmlerini karşılaştırmayı amaçladık. Çalışmaya, 22 voleybol sporcusu (yaş: 21.59 ± 2.70 yıl; boy: 1.87 ± 7.92 m; vücut ağırlığı: 80.99 ± 8.14 kg; vücut yağı: 12.05 ± 5.78%) gönüllü olarak katıldı. Bukkal epitel hücrelerinden DNA ekstraksiyonu ticari bir kit ile sağlandı. Genotipleme için Real-Time PCR yapıldı. Test sonuçlarının istatistiksel analizi SPSS 23 (SPSS Inc., Chicago, IL, ABD) paket programı kullanılarak yapıldı. Varyans homojenliği Levenne testi ile analiz edildi ve normal dağılım Shapiro-Wilk testi ile analiz edildi. Tüm parametreleri analiz etmek için One Way ANOVA Testi kullanıldı. Anlamlılık pIn this study, we aimed to compare ACTN3 rs1815739, PPARA rs4253778 and IL-6 rs1800795 polymorphisms with aerobic endurance in volleyball players. Twenty-two volleyball players (age: 21.59 ± 2.70 years; height: 1.87 ± 7.92 m; body weight: 80.99 ± 8.14 kg; body fat: 12.05 ± 5.78%) participated in the study voluntarily. DNA extraction from buccal epithelial cells was provided by a commercial kit. Real-Time PCR was performed for genotyping. Statistical analysis of the test results was performed using SPSS 23 (SPSS Inc., Chicago, IL, USA) package program. Homogeneity of variance was analyzed by Levenne test and normal distribution was analyzed by Shapiro-Wilk test. One Way ANOVA Test was used to analyze all parameters. Significance was determined at p0.05). In the findings, no statistically significant difference was detected between the relevant polymorphisms and aerobic performance parameters in our cohort. In conclusion, ACTN3 rs1815739, PPARA rs4253778 and IL6 rs1800795 genes did not create any difference in aerobic endurance in volleyball players. Our results need to be confirmed by further studies.