Green Synthesis, Characterization and Determination of Biological Activity of Sunflower Honey Based-Silver Nanoparticles

Abstract

Nanoparticles such as gold, silver, zinc, which are the building blocks of nanotechnology, which have a wide range of applications in medicine, drug release systems, pharmacy, agriculture, can be synthesized in an environmentally friendly, economical and biocompatible way using green synthesis technique. In the green synthesis of silver nanoparticles, plants or plant-based products are widely used due to the bioactive components they contain. Honey is one of the important natural products that can be used in the synthesis of silver nanoparticles with its phenolic components and sugars. In this study, the potential of sunflower honey, which is weaker than chestnut and oak honey in terms of bioactive components, for the synthesis of silver nanoparticles was determined. The synthesized sunflower honey-based silver nanoparticles (SH-AgNPs) were characterized and then their antioxidant activity and inhibition of myeloperoxidase and collagenase enzymes, which play an important role in wound healing, were determined. It was determined that the synthesized nanoparticles gave maximum absorbance at 440 nm and particle sizes ranged between 33 nm and 38 nm. The DPPH- radical scavenging activities and ferric reducing capacity (FRAP) of the synthesized nanoparticles were determined as 81 ±1.42% and 86±1.24%, respectively, and the inhibition properties of myleoperoxidase and collagenase enzymes were determined as 63±1.45% and 37±1.14%, respectively. The findings obtained show that sunflower honey has the potential for use in the field of nanotechnology. © 2024 Bursa Uludag University. All rights reserved.